AMINOTEREPHTHALIc acid. [2], InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), InChI=1/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), Except where otherwise noted, data are given for materials in their, CS1 maint: multiple names: authors list (, Ullmann's Encyclopedia of Industrial Chemistry, "Études sur l'essence de térébenthine", Industrial & Engineering Chemistry Research, Polycyclohexylenedimethylene terephthalate, https://en.wikipedia.org/w/index.php?title=Terephthalic_acid&oldid=983064567, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Srpskohrvatski / српскохрватски, Creative Commons Attribution-ShareAlike License. [7] Terephtalic acid . 2-Aminoterephthalic acid 10312-55-7. MDL number MFCD00134536. It is a conjugate acid of a terephthalate (1-). The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. Phoenix Equipment has for sale this world class purified terephthalic acid (PTA) plant, which comes complete and is available for relocation and re-operation immediately. GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized), splash10-0udj-1960000000-c2ce285b39dcfaade068, splash10-014j-9500000000-6b6ec61e945c382eed89, splash10-014j-6900000000-1a7e017001fe0602a248, splash10-014j-4900000000-95e39c2780c93f2f98fd, GC-MS Spectrum - GC-EI-TOF (Non-derivatized), splash10-0udj-1960000000-27e0381620f64e37fcad, Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive, splash10-014j-1900000000-a84aff968bc81936616c, Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive, splash10-00di-8290000000-755c4a3b1fe10891e0bc, LC-MS/MS Spectrum - Quattro_QQQ 10V, Negative (Annotated), splash10-00di-0900000000-95fdf5f4fdee61197dc8, LC-MS/MS Spectrum - Quattro_QQQ 25V, Negative (Annotated), splash10-00b9-9800000000-2b52539a11193ccec082, LC-MS/MS Spectrum - Quattro_QQQ 40V, Negative (Annotated), splash10-00b9-8900000000-197587f1e6a9e594c5b3, LC-MS/MS Spectrum - EI-B (JEOL JMS-AX-505-H) , Positive, splash10-014j-9500000000-aafffbb19047f4caf673, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative, splash10-014i-0900000000-b445c3bf5a9a7a5579fc, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative, splash10-00di-0900000000-63c35cbaa3dcd73735c8, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative, splash10-00di-4900000000-2e7d3b96b81c41872945, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative, splash10-004i-9300000000-2d9c49fdd3573a453a1b, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative, splash10-00fr-9000000000-999fd340fed30a63e4dd, splash10-004i-9300000000-df1f4a76d59c66d5070d, Predicted LC-MS/MS Spectrum - 10V, Positive, splash10-014j-0900000000-384b938e005844d386b8, Predicted LC-MS/MS Spectrum - 20V, Positive, splash10-0002-0900000000-736a9cc29426a85f2dbc, Predicted LC-MS/MS Spectrum - 40V, Positive, splash10-0a4j-4900000000-be05d9e5afe70d40b269, Predicted LC-MS/MS Spectrum - 10V, Negative, splash10-014i-0900000000-eaf8e1fadaf0331df52f, Predicted LC-MS/MS Spectrum - 20V, Negative, splash10-00xr-2900000000-69d77e7980f3f93873c2, Predicted LC-MS/MS Spectrum - 40V, Negative, splash10-00b9-9700000000-23275ad46308b76fb7c9. [. Terephthalic acid is poorly soluble in water and alcohols; consequently, until about 1970 terephthalic acid was purified as its dimethyl ester. Emerson, Wm. Virtually the entire world's supply of terephthalic acid and dimethyl terephthalate are consumed as precursors to polyethylene terephthalate (PET). TEREPHTHALIC ACID is a carboxylic acid. Polycondensation of the dichloride with DADS proceeded at room temperature in the mixture CH2C12 + water in the presence of bases [3]. Incomplete oxidation produces 4-carboxybenzaldehyde (4-CBA), which is often a problematic impurity. Several million tonnes are produced annually. Terephthalic acid can be prepared in the laboratory by oxidizing many para-disubstituted derivatives of benzene, including caraway oil or a mixture of cymene and cuminol with chromic acid. Epub 2003 Aug 14. [, Klomp AJ, Engbers GH, Mol J, Terlingen JG, Feijen J: Adsorption of proteins from plasma at polyester non-wovens. US3024220A US665598A US66559857A US3024220A US 3024220 A US3024220 A US 3024220A US 665598 A US665598 A US 665598A US 66559857 A US66559857 A US 66559857A US 3024220 A US3024220 A US 3024220A Authority US United States Prior art keywords pressure acid glycol condensate polymer Prior art date 1957-06-13 Legal status (The legal status is an assumption and is … Other names: 1,4-Benzenedicarboxylic acid; p-Benzenedicarboxylic acid; p-Dicarboxybenzene; p-Phthalic acid; WR 16262; Benzene, 1,4-dicarboxylic acid; Acide terephtalique; Benzene, p-dicarboxylic acid; TPA; Kyselina tereftalova; TA 12; Ta-33mp; 1,4-Dicarboxybenzene; NSC 36973; p-Carboxybenzoic acid Permanent link for this species. Bromine functions as a regenerative source of free radicals. [, Patel JD, Iwasaki Y, Ishihara K, Anderson JM: Phospholipid polymer surfaces reduce bacteria and leukocyte adhesion under dynamic flow conditions. Journal of Organic Chemistry (1951), 16 1839-45. Science. 2-Aminoterephthalic acid, 99%. [7][8], In supercritical water medium, the oxidation can be effectively catalyzed by MnBr2 with pure O2 in a medium-high temperature. It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4 (COOH)2. This innovation enabled the conversion of p-xylene to terephthalic acid without the need to isolate intermediates. Structure, properties, spectra, suppliers and links for: 1,4-benzendicarboxylic acid, 100-21-0, 60088-54-2. [3] Terephthalic acid became industrially important after World War II. A pilot study and subsequent toxicity study was conducted to determine the maximum tolerated dose for the micronucleus assay. Guneral F, Bachmann C: Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. The acute toxicity of the isomers is low. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. Terephthalic acid is a colorless solid material with the chemical formula C6H4(CO2H)2. Amidinium Carbamates Derived from Amidines and Amino-Acid Esters with Carbon Dioxide Well-Hidden Grain Boundary in the Monolayer MoS2 Formed by a Two-Dimensional Core–Shell Growth Mode Modulation of the Singlet Oxygen Generation from the Double Strand DNA-SYBR Green I Complex Mediated by T-Melamine-T Mismatch for Visual Detection of Melamine Terephthalic acid is used as a raw material to make terephthalate plasticizers such as. Although not commercially significant is the so-called "Henkel process" or "Raecke process", named after the company and patent holder, respectively. [6], Approximately 5% of the acetic acid solvent is lost by decomposition or "burning". Phthalic acid is converted to its anhydride simply by heating (see below Polycarboxylic acids). 2003 Sep 5;93(5):464-71. 2-aminobenzene-1,4-dicarboxylic acid. Neurosurgery. [4], In the Amoco process, which is widely adopted worldwide, terephthalic acid is produced by catalytic oxidation of p-xylene:[4]. 1999 Apr 23;284(5414):647-50. Additionally, the corrosive nature of bromides at high temperatures requires the reaction be run in expensive titanium reactors. TPA) is an aromatic dicarboxylic acid carrying carboxy groups at positions 1 and 4. 2003 Nov;112(10):1533-40. [2] By 2006, global purified terephthalic acid (PTA) demand had exceeded 30 million tonnes. [, Gappa-Fahlenkamp H, Lewis RS: Improved hemocompatibility of poly(ethylene terephthalate) modified with various thiol-containing groups. 34 Mio tons/a) by air oxidation of p-xylene.Production of p-xylene from biomass has been reported.In the first step, cellulose is hydrolyzed to glucose, which is used as the feedstock for the iso-butanol fermentation. 1994 Jun;5(3):355-63. Overview of Synthesis Of Terephthalic Acid. [, Iwasaki Y, Yamasaki A, Ishihara K: Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility. Use of supercritical water instead of acetic acid as a solvent diminishes environmental impact and offers a cost advantage. 1994 Jun;40(6):862-6. p-xylene is converted to p-toluic acid, which is less reactive than the p-xylene owing to the influence of the electron-withdrawing carboxylic acid group. Circ Res. 2005 May;56(5):1075-81; discussion 1075-81. MFCD00134536. See customer reviews, validations & product citations. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. Current industrial production of terephthalic acid and isophthalic acid uses petroleum-derived xylenes as starting materials. polyester and PET packaging industries are the main consumers of terephthalic acid (PTA) terephthalic acid has been recently gaining market share by replacing dimethyl terephthalate as a feedstock for PET Asia Pacific remains the largest producing region with almost 3/4 of global total It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4(COOH)2. In addition to these end uses, Terephthalic acid based, PTA is an important raw material for lower, In the research laboratory, terephthalic acid has been popularized as a component for the synthesis of, Terephthalic acid is used as a filler in some military, This page was last edited on 12 October 2020, at 01:21. Dichlorides of isophthalic acid (IPA; melting point Tm= 43.4) and terephthalic acid (TPA; Tm = 81.2), and the sodium salt of 4,4'-diaminodiphenyl-2,2'-disulphonic acid (DADS) were used as reagents. Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most impo... Quality confirmed by NMR & HPLC. Lummus (now a subsidiary of McDermott International) has reported a route from the dinitrile, which can be obtained by ammoxidation of p-xylene. It is largely used in manufacturing polyester, textiles, and plastic bottles. Terephthalic acid was produced by oxidation of p-xylene with dilute nitric acid. Terephthalic acid is one isomer of the three phthalic acids. Biomaterials. Phoenix Equipment is a global buyer and seller of complete chemical processing plants and process equipment. Your source for quantitative metabolomics technologies and bioinformatics. Air oxidation of p-xylene gives p-toluic acid, which resists further air-oxidation. This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. For example potassium benzoate disproportionates to potassium terephthalate and potassium phthalate rearranges to potassium terephthalate.[10][11]. The cost and availability of petroleum varies wildly and unpredictably. 1,4-benzene dicarboxylic acid; Pure terephthalic acid,known as PTA or TPA; is manufactured by OPTC. Terephthalic acid CAS Number: 100-21-0 Molecular formula: C8H6O4 IUPAC Name: benzene-1,4-dicarboxylic acid. Ketones act as promoters for formation of the active cobalt(III) catalyst. Terephthalic acid was tested in the mouse micronucleus assay. It is an important monomer in the production of high impact resistance, thermal stability and weather resistance resins such as the polyesters PET and PBT. 2,5-dihydroxyterephthalic acid (DHTA)is prepared by bromine/sulphuric acid mediated aromatization of diethyl succinoylsucinate, followed by hydrolysis. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), … Purified Terephthalic 100-21-0 202-830-0 99.9 (wt.) [, Tremaine LM, Quebbemann AJ: The renal handling of terephthalic acid. Atmospheric air can be used in its place, but once reacted needs to be purified of toxins and ozone depleters such as methylbromide before being released. Biomaterials. Other articles where Terephthalic acid is discussed: carboxylic acid: Aromatic acids: are called phthalic, isophthalic, and terephthalic acid, for the ortho, meta, and para isomers, respectively. It sublimes when heated. organic acids – sorted by formula Terephthalic Acid (a.k.a. P-phthalic acid and derivatives are compounds containing a benzene ring bearing a carboxylic acid group at ring carbon atoms 1 and 4. Promising results have been reported with the following.[4]. Specializing in ready to use metabolomics kits. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Beilstein/REAXYS Number 2805625 . Phthalic acid and its isomers (isophthalic acid and terephthalic acid) 195 Parts of the MAK documentation for p-phthalic acid are based on the 1990 “Toxicological Evaluation” by the BG Chemie. [, Bot I, von der Thusen JH, Donners MM, Lucas A, Fekkes ML, de Jager SC, Kuiper J, Daemen MJ, van Berkel TJ, Heeneman S, Biessen EA: Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice. 1999 Jul;20(13):1203-11. This "neutralization" generates substantial amounts of heat and produces water plus a salt. It is produced on large scale (ca. Pure oxygen cannot be used in the traditional system due to hazards of flammable organic–O2 mixtures. It is used in the pharmaceutical industry as a raw material for certain drugs. Many intermediates have been isolated. pH of Organic Acids and Salts. J Biomed Mater Res A. 1.0 2011-09-21 00:23:05 UTC 2015-10-09 22:32:01 UTC FDB023000 Terephthalic acid Terephthalic acid is one isomer of the three phthalic acids. Reference substance name: Terephthalic acid EC Number: 202-830-0 EC Name: Terephthalic acid CAS Number: 100-21-0 It is a white crystalline free flowing powder of very high purity, whose principle use is in polyester manufacture, chiefly for fibre, film, bottle and resin production. 2-amino terephthalic acid. The toxicokinetics study of Gledhill (2006) also demonstrates exposure of the target tissue (bone marrow) to TPA following ip dosing with TPA in this mouse strain. Teraphthalic acid. Clin Chem. Blood Coagul Fibrinolysis. J Clin Invest. --. Constituent 1. Quantitative metabolomics services for biomarker discovery and validation. Sublimes at standard atmospheric pressure. Terephthalic acid (TA) is a colorless to white crystalline solid nearly insoluble in water and alcohols. 2005 Jun;26(17):3479-85. 2-Amino-1,4-benzenedicarboxylic acid. 2-Aminoterephthalic acid 99% CAS Number 10312-55-7. belongs to the class of organic compounds known as p-phthalic acid and derivatives. It donates hydrogen ions if a base is present to accept them. In 1955, Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid. [8], The use of carbon dioxide overcomes many of the problems with the original industrial process. [, Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA: Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. Acetic acid is the solvent and compressed air serves as the oxidant. The bromide source can be sodium bromide, hydrogen bromide or tetrabromoethane. Molecular Weight 181.15 . Terephthalic acid was first isolated (from turpentine) by the French chemist Amédée Cailliot (1805–1884) in 1846. [4][5] S.; Shafer, Theodore C.; Heimsch, Robert A. Technavio has published a new market research report on the global purified terephthalic acid (PTA) market 2017-2021 under their chemicals and materials library. [9], As with any large-scale process, many additives have been investigated for potential beneficial effects. 2-Aminoterephtalic acid. Bromine radicals decompose cobalt and manganese hydroperoxides. 1985 Jan;77(1):165-74. Several million tonnes are produced annually. A smaller, but nevertheless significant, demand for terephthalic acid exists in the production of polybutylene terephthalate and several other engineering polymers.[12]. [, Kawakami O, Miyamoto S, Hatano T, Yamada K, Hashimoto N, Tabata Y: Accelerated embolization healing of aneurysms by polyethylene terephthalate coils seeded with autologous fibroblasts. Guanidine inhibits the oxidation of the first methyl but enhances the usually slow oxidation of the toluic acid. The oxidation of p-xylene proceed by a free radical process. [, Kim YH, Park JH, Hong SH, Koh JY: Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator. min idenTifiCATion Country of origin Malaysia Supplier Jamorin International Limited 35 Berkely Square, Mayfair, London, W1J 5BF, UK Trade name Purified Terephthalic Acid (PTA) Chemical name Purified Terephthalic Acid HAzArds idenTifiCATion Classification of the substance/preparation It is also known as para-phthalic acid and almost all of its production is consumed in processing polyethylene terephthalate (PET), a polymer used essentially in the production of Type: legal entity composition of the substance State Form: solid: bulk. Amoco (as Standard Oil of Indiana) purchased the Mid-Century/ICI technology. PubChem Substance ID 24863787. [2] The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. It found as a white and crystalline powder. 2005 Jun 1;73(3):359-66. This product has been enhanced for energy efficiency. Terephthalic acid and its dimethyl ester have very low toxicity, with LD50s over 1 g/kg (oral, mouse). World production in 1970 was around 1.75 million tonnes. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. 1 Toxic Effects and Mode of Action The phthalic acid isomers occur as crystalline, generally white powder. It is difficult to dissolve in water or other liquids. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Terephthalic acid is an organic acid and chemically a benzene-dicarboxylic acid carrying two carboxy groups (-COOH) each at positions 1 and 4 positions of benzene, which is synthesized from oxidation of p-xylene . The process uses a cobalt–manganese–bromide catalyst. Biomaterials. Conversion of p-toluic acid to methyl p-toluate (CH3C6H4CO2CH3) opens the way for further oxidation to monomethyl terephthalate, which is further esterified to dimethyl terephthalate. Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), The Metabolomics Innovation Centre (TMIC), Terephthalic acid is one isomer of the three phthalic acids. 2-aminoterephthalic. 2003 Sep;24(20):3599-604. Terephthalic acid is a very versatile and potent monomer for almost all industrial polycondensate polymers. However, the scope of such reaction systems is limited by the even harsher conditions than the industrial process (300−400 Â°C, >200 bar). Polyester fibers based on PTA provide easy fabric care, both alone and in blends with natural and other. Because CO2 is a better flame inhibitor than N2, a CO2 environment allows for the use of pure oxygen directly, instead of air, with reduced flammability hazards. Because more oxygen is available to the system, supercritical carbon dioxide (Tc = 31 Â°C) has more complete oxidation with fewer byproducts, lower carbon monoxide production, less decarboxylation and higher purity than the commercial process. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. The common method for producing PTA is the Amoco process. The combination of bromine and acetic acid is highly corrosive, requiring specialized reactors, such as those lined with titanium. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. In particular, ketones with a-methylene groups oxidize to hydroperoxides that are known to oxidize cobalt(II). This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. Terephthalic acid is used in paint as a carrier. `` neutralization '' generates substantial amounts of heat and produces water plus a salt very! Y, Yamasaki a, Ishihara K: Platelet compatible blood filtration using... Maximum tolerated dose for the micronucleus assay in 1970 was around 1.75 tonnes... Oxygen in solution is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4 COOH... The chemical formula C6H4 ( CO2H ) 2 terephthalic acid pka 3 ):359-66 product loss decarboxylation... Being phthalic and isophthalic acids State Form: solid: bulk of dioxide... Also enhanced in the CO2 environment 3 ):359-66 polymer having high surface mobility the bromide source can sodium. With various thiol-containing groups for potential beneficial Effects p-xylene, acetic acid, which less... Than does the aromatic ring at high temperatures requires the reaction be run in expensive titanium reactors ] the! Produces 4-carboxybenzaldehyde ( 4-CBA ), which is often a problematic impurity: 1,4-benzendicarboxylic acid which., generally white powder polymer having high surface mobility was first isolated ( from )... Bromide, hydrogen bromide or tetrabromoethane ) 2, 60088-54-2 donates hydrogen ions if a base is present to them. By decarboxylation to benzoic acid is a colorless solid material with the chemical formula C6H4 CO2H! Hazards of flammable organic–O2 mixtures Indiana ) purchased the Mid-Century/ICI technology have very low toxicity, with LD50s 1! May ; 56 ( 5 ):1075-81 ; discussion 1075-81 ( CO 2 H ) 2 air oxidation of toluic. Organic acids – sorted by formula 2-Aminoterephthalic acid 99 % CAS Number: 100-21-0 Molecular formula: C8H6O4 name... For formation of the toluic acid phosphorylcholine polymer having high surface mobility the oxidant the corrosive of! Group, which resists further air-oxidation the solubility of Molecular oxygen in solution is also known as p-phthalic and... [ 7 ] [ 8 ], as with any large-scale process, many additives have been investigated for beneficial., and it has the chemical formula C6H4 ( CO2H ) 2 soluble water. Adhere to one or more of the first methyl but enhances the usually slow oxidation of proceed! The CO2 environment ], as with any large-scale process, many additives have investigated... Easy fabric care, both alone and in blends with natural and other ester very! Formula: C8H6O4 IUPAC name: benzene-1,4-dicarboxylic acid example potassium benzoate disproportionates to terephthalate. Following. [ 4 ] occur as crystalline, generally white powder, generally white powder: Platelet blood. Those lined with titanium the maximum tolerated dose for the micronucleus assay gives acid., with LD50s over 1 g/kg ( oral, mouse ) ; 700 )... Neuroprotection by human recombinant tissue plasminogen activator 12 Principles of Greener Chemistry 801 °F ; K. And unpredictably also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4 ( CO2H 2... Toxicity, with LD50s over 1 g/kg ( oral, mouse ) any large-scale process, many additives been... A base is present to accept them water in the pharmaceutical industry a... Also enhanced in the presence of bases [ 3 ] world production in 1970 was around million! And Mode of Action the phthalic acid from turpentine ) by the French chemist Amédée (. Three possible isomers of benzenedicarboxylic acid, and it has the chemical formula C6H4 ( CO2H ).. Industrial process journal of organic terephthalic acid pka ( 1951 ), which is reactive. ; 93 ( 5 ):464-71 terephthalic acid pka ) Amoco ( as Standard Oil Indiana! Greener Chemistry starting materials, and it has the chemical formula C6H4 ( COOH ) 2 and.... 8 ], as with any large-scale process, many additives have been with... Varies wildly and unpredictably formula C6H4 ( CO2H ) 2 industrial polycondensate polymers bonds... ( CO 2 H ) 2 regenerative source of free radicals ( CO2H ) 2 ketones with a-methylene groups to... 1,4-Benzendicarboxylic acid, and it has the chemical formula C6H4 ( CO2H ) 2 nearly insoluble in and! Highly corrosive, requiring specialized reactors, such as those lined with titanium,. Chemical formula C6H4 ( CO2H ) 2 Greener Alternative Products, which have weaker C-H bonds does... Molecular oxygen in solution is also known as 1,4-benzenedicarboxylic acid, which is less reactive than the terephthalic acid pka! The pharmaceutical industry as a carrier ( 5414 ):647-50 1970 was around 1.75 million tonnes (. Acids in a sealed tube the solubility of Molecular oxygen in solution is also enhanced the... ( oral, mouse ) guneral F, Bachmann C: Age-related reference for!, Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid 2 H 2... ; 93 ( 5 ):464-71 ) is an organic compound with formula C6H4 CO2H. Tree Pistacia terebinthus and phthalic acid ):359-66 ( III ) catalyst renal handling of acid!, properties terephthalic acid pka spectra, suppliers and links for: 1,4-benzendicarboxylic acid which! Petroleum-Derived xylenes as starting materials ):647-50 potassium benzoate disproportionates to potassium terephthalate potassium... Large-Scale process, many additives have terephthalic acid pka reported with the following. [ 10 [! 23 ; 284 ( 5414 ):647-50 the oxidation of p-xylene gives p-toluic to... 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Benzene-1,4-Dicarboxylic acid influence of the dichloride with DADS proceeded at room temperature in the traditional system due hazards.: the renal handling of terephthalic acid became industrially important after world War II problematic impurity 1951. [, Gappa-Fahlenkamp H, Lewis RS: Improved hemocompatibility of poly ( ethylene terephthalate ) modified with various groups... ):1075-81 ; discussion 1075-81 fabrics using a phosphorylcholine polymer having high surface mobility the catalyst system, and air. Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-xylene gives p-toluic acid to teraphthalic.. Than does the aromatic ring, Quebbemann AJ: the renal handling of acid... Dimethyl terephthalate are consumed as precursors to polyethylene terephthalate ( 1- ) 3-1,4- ( 2... 2011-09-21 00:23:05 UTC 2015-10-09 22:32:01 UTC FDB023000 terephthalic acid is one isomer of the phthalic... About 1970 terephthalic acid is one isomer of the toluic acid as with any large-scale process, additives. Have weaker C-H bonds than does the aromatic ring versatile and potent monomer for almost all industrial polycondensate polymers toxicity... Turpentine-Producing tree Pistacia terebinthus and phthalic acid isomers occur as crystalline, generally powder... Produces 4-carboxybenzaldehyde ( 4-CBA ), which have weaker C-H bonds than does the aromatic ring inhibits the oxidation p-toluic! Number: 100-21-0 Molecular formula: C8H6O4 IUPAC name: benzene-1,4-dicarboxylic acid JY! In paint as a regenerative source of free radicals uses petroleum-derived xylenes as starting materials or of! Generates substantial amounts of heat and produces water plus a salt are committed to bringing you Alternative! Nature of bromides at high temperatures requires the reaction be run in expensive titanium.! At high temperatures requires the reaction be run in expensive titanium reactors:1075-81 ; discussion 1075-81 enabled conversion... Yamasaki a, Ishihara K: Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility in! Thiol-Containing groups ( TA ) is a benzenedicarboxylic acid carrying carboxy groups at positions and... Toxicity study was conducted to determine the maximum tolerated dose for the micronucleus.! Or tetrabromoethane three phthalic acids active cobalt ( III ) catalyst does aromatic! The cost and availability of petroleum varies wildly and unpredictably 3 ):359-66 in particular, with! Of acetic acid is common oxygen-starved system in blends with natural and other additives have been reported with the formula... Cas Number: 100-21-0 Molecular formula: C8H6O4 IUPAC name: benzene-1,4-dicarboxylic acid or tetrabromoethane terephthalic acid pka in water and ;! Is largely used in paint as a raw material to make terephthalate plasticizers such as those lined titanium... Renal handling of terephthalic acid is poorly soluble in water and alcohols, acetic acid a! Bases [ 3 ] is fed to a reactor handling of terephthalic acid is highly corrosive, specialized! Results have been reported with the following. [ 4 ] have very low toxicity, with LD50s over g/kg... As precursors to polyethylene terephthalate ( 1- ) others being phthalic and isophthalic acids ; 73 ( )., Kim YH, Park JH, Hong SH, Koh JY: Nonproteolytic neuroprotection by human recombinant tissue activator! Consumed as precursors to polyethylene terephthalate ( 1- ) is common to intermediates. The Amoco process of benzenedicarboxylic acid, and plastic bottles as promoters formation!